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Influência dos corticosteroides no prognóstico auditivo da perda auditiva neurossensorial súbita idiopática

机译:糖皮质激素对突发性特发性感音神经性听力损失的听觉预后的影响

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摘要

INTRODUCTION:Idiopathic Sudden Sensorineural Hearing Loss (ISSHL) is defined when a loss of at least 30 dB occurs in over 3 continuous frequencies, in up to 72 hours, of which etiology is not established, despite adequate investigation. Different types of treatment regimens have been proposed, but only glucocorticoids have shown some evidence of benefit in the literature.OBJECTIVE:To analyze whether the type of treatment or time of treatment with glucocorticoids have any influence on hearing recovery in ISSHL.METHODS:Observational retrospective cohort study. One hundred twenty-seven patients with ISSHL, treated at outpatient clinics between the years 2000 and 2010, were studied. We evaluated the prognostic correlation of the type of treatment and time to treatment with glucocorticoids and ISSHL.RESULTS:The absolute hearing gain and the relative hearing gain was as follows: 23.6 dB and 37.2%. Complete recovery was observed in 15.7% of patients, significant recovery in 27.6% and recovery in 57.5%.CONCLUSION:In this study, there was no difference between the use and nonuse of glucocorticoids in hearing improvement. However, when started within seven days after onset, the use of glucocorticoids was a factor of better prognosis.
机译:简介:定义为特发性突然感觉神经性听力损失(ISSHL)是指在连续72个小时内的3个以上连续频率中至少发生30 dB的损失,尽管进行了充分的研究,但仍未确定病因。提出了不同类型的治疗方案,但文献中仅糖皮质激素显示出有益的证据。目的:分析糖皮质激素的治疗​​类型或治疗时间是否对ISSHL的听力恢复有任何影响。方法:观察性回顾性队列研究。研究对象为2000年至2010年间在门诊接受治疗的127名ISSHL患者。我们评估了糖皮质激素和ISSHL治疗类型和治疗时间的预后相关性。结果:绝对听力增益和相对听力增益如下:23.6 dB和37.2%。结论:在15.7%的患者中完全康复,在27.6%的患者中显着康复,在57.5%的患者中康复。结论:在这项研究中,糖皮质激素的使用与不使用之间在听力改善方面没有差异。但是,在发病后7天内开始使用糖皮质激素是改善预后的一个因素。

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